• Persistence of Robust Humoral Immune Response in Coronavirus Disease 2019 Convalescent Individuals Over 12 Months After Infection.
  Miyakawa K, Kubo S, Stanleyraj Jeremiah S, Go H, Yamaoka Y, Ohtake N, Kato H, Ikeda S, Mihara T, Matsuba I, Sanno N, Miyakawa M, Shinkai M, Miyazaki T, Ogura T, Ito S, Kaneko T, Yamamoto K, Goto A, Ryo A. Open Forum Infect Dis. 2021 Dec 10;9(2):ofab626.
   

• Detailed Evolutionary Analyses of the F Gene in the Respiratory Syncytial Virus Subgroup A.
  Saito M, Tsukagoshi H, Sada M, Sunagawa S, Shirai T, Okayama K, Sugai T, Tsugawa T, Hayashi Y, Ryo A, Takeda M, Kawashima H, Saruki N, Kimura H. Viruses. 2021 Dec 15;13(12):2525.
   

• Evaluation of four phosphopeptide enrichment strategies for mass spectrometry-based proteomic analysis. 
  Ino Y, Kinoshita E, Kinoshita-Kikuta E, Akiyama T, Nakai Y, Nishino K, Osada M, Ryo A, Hirano H, Koike T, Kimura Y. Proteomics. 2021 Dec 21:e2100216.
   

• Antibody titers against the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2 induced by BNT162b2 vaccination measured using automated chemiluminescent enzyme immunoassay.
  Kato H, Miyakawa K, Ohtake N, Go H, Yamaoka Y, Yajima S, Shimada T, Goto A, Nakajima H, Ryo A. J Infect Chemother. 2021 Nov 29:S1341-321X(21)00332-9. 
   

• Identification of serum prognostic biomarkers of severe COVID-19 using a quantitative proteomic approach.
  Kimura Y, Nakai Y, Shin J, Hara M, Takeda Y, Kubo S, Jeremiah SS, Ino Y, Akiyama T, Moriyama K, Sakai K, Saji R, Nishii M, Kitamura H, Murohashi K, Yamamoto K, Kaneko T, Takeuchi I, Hagiwara E, Ogura T, Hasegawa H, Tamura T, Yamanaka T, Ryo A. Sci Rep. 2021 Oct 19;11(1):20638.
   

• HERC5 E3 ligase mediates ISGylation of hepatitis B virus X protein to promote viral replication.
  Bawono RG, Abe T, Qu M, Kuroki D, Deng L, Matsui C, Ryo A, Suzuki T, Matsuura Y, Sugiyama M, Mizokami M, Shimotohno K, Shoji I. J Gen Virol. 2021 Oct;102(10).
   

• Capsid Allosteric Modulators Enhance the Innate Immune Response in Hepatitis B Virus-Infected Hepatocytes During Interferon Administration.
  Fukutomi K, Hikita H, Murai K, Nakabori T, Shimoda A, Fukuoka M, Yamai T, Higuchi Y, Miyakawa K, Suemizu H, Ryo A, Yamada R, Kodama T, Sakamori R, Tatsumi T, Takehara T. Hepatol Commun. 2021 Aug 25. doi: 10.1002/hep4.1804.
   

• HBx-induced degradation of Smc5/6 complex impairs homologous recombination-mediated repair of damaged DNA.
  Sekiba K, Otsuka M, Funato K, Miyakawa Y, Tanaka E, Seimiya T, Yamagami M, Tsutsumi T, Okushin K, Miyakawa K, Ryo A, Koike K. J Hepatol. 2021 Aug 25:S0168-8278(21)02005-5.
   

• All-Trans Retinoic Acid Exhibits Antiviral Effect against SARS-CoV-2 by Inhibiting 3CLpro Activity.
  Morita T, Miyakawa K, Jeremiah SS, Yamaoka Y, Sada M, Kuniyoshi T, Yang J, Kimura H, Ryo A. Viruses. 2021 Aug 23;13(8):1669.
   

• Rapid detection of neutralizing antibodies to SARS-CoV-2 variants in post-vaccination sera.
  Miyakawa K, Stanleyraj JS, Kato H, Yamaoka Y, Go H, Yajima S, Shimada T, Mihara T, Goto A, Yamanaka T, Ryo A. J Mol Cell Biol. 2021 Aug 27:mjab050.
   

• Evaluation of a combination protocol of CT-first triage and active telemedicine methods by a selected team tackling COVID-19: An experimental research study. 
  Miyake S, Higurashi T, Kato H, Yamaoka Y, Kessoku T, Kato S, Ogawa F, Oi Y, Nakajima A, Yamamoto T, Takeuchi I, Ryo A, Maeda S. J Infect Public Health. 2021 Aug 18;14(9):1212-1217.

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• Inhibitory effect of a novel thiazolidinedione derivative on hepatitis B virus entry.

　   Tanaka T, Okuyama-Dobashi K, Motohashi R, Yokoe H, Takahashi K, Wiriyasermkul P, Kasai H, Yamashita A,      

      Maekawa S, Enomoto N, Ryo A, Nagamori S, Tsubuki M, Moriishi K. Antiviral Res. 2021 Aug 19;194:105165.

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• Combining IL-6 and SARS-CoV-2 RNAaemia-based risk stratification for fatal outcomes of COVID-19.
  Saji R, Nishii M, Sakai K, Miyakawa K, Yamaoka Y, Ban T, Abe T, Ohyama Y, Nakajima K, Hiromi T, Matsumura R, Suzuki N, Taniguchi H, Otsuka T, Oi Y, Ogawa F, Uchiyama M, Takahashi K, Iwashita M, Kimura Y, Fujii S, Furuya R, Tamura T, Ryo A, Takeuchi I.PLoS One. 2021 Aug 11;16(8):e0256022.

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• Development of highly sensitive and rapid antigen detection assay for diagnosis of COVID-19 utilizing optical waveguide immunosensor. 
  Funabashi R, Miyakawa K, Yamaoka Y, Yoshimura S, Yamane S, Jeremiah SS, Shimizu K, Ozawa H, Kawakami C, Usuku S, Tanaka N, Yamazaki E, Kimura H, Hasegawa H, Ryo A. J Mol Cell Biol. 2021 Jun 24:mjab037.

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• Highly specific monoclonal antibodies and epitope identification against SARS-CoV-2 nucleocapsid protein for antigen detection tests.
  Yamaoka Y, Miyakawa K, Jeremiah SS, Funabashi R, Okudela K, Kikuchi S, Katada J, Wada A, Takei T, Nishi M, Shimizu K, Ozawa H, Usuku S, Kawakami C, Tanaka N, Morita T, Hayashi H, Mitsui H, Suzuki K, Aizawa D, Yoshimura Y, Miyazaki T, Yamazaki E, Suzuki T, Kimura H, Shimizu H, Okabe N, Hasegawa H, Ryo A. Cell Rep Med. 2021 May 16:100311.

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• Sustained Neutralizing Antibodies 6 Months Following Infection in 376 Japanese COVID-19 Survivors.
  Goto A, Go H, Miyakawa K, Yamaoka Y, Ohtake N, Kubo S, Jeremiah SS, Mihara T, Senuki K, Miyazaki T, Ikeda S, Ogura T, Kato H, Matsuba I, Sanno N, Miyakawa M, Ozaki H, Kikuoka M, Ohashi Y, Ryo A, Yamanaka T. Front Microbiol. 2021 May 7;12:661187.

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• Cleavage of TANK-Binding Kinase 1 by HIV-1 Protease Triggers Viral Innate Immune Evasion.
  Jeremiah SS, Miyakawa K, Matsunaga S, Nishi M, Kudoh A, Takaoka A, Sawasaki T, Ryo A. Front Microbiol. 2021 Apr 27;12:643407.

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• Carbonic anhydrase 13 suppresses bone metastasis in breast cancer.
  Yogosawa S, Nakayama J, Nishi M, Ryo A, Yoshida K. Cancer Treat Res Commun. 2021 Feb 9;27:100332.

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•  Severe acute respiratory syndrome coronavirus 2 prevalence in saliva and gastric and intestinal fluid in patients undergoing gastrointestinal endoscopy in coronavirus disease 2019 endemic areas: Prospective cross-sectional study in Japan. 
  Miyake S, Ashikari K, Kato S, Takatsu T, Kuwashima H, Kaneko H, Nagai K, Watari I, Sato T, Yamaoka Y, Yamamoto T, Ryo A, Maeda S, Nakajima A, Higurashi T. Dig Endosc. 2021 Feb 6. doi: 10.1111/den.13945. Epub ahead of print. PMID: 33548095.

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• Development of an Automated Chemiluminescence Assay System for Quantitative Measurement of Multiple Anti-SARS-CoV-2 Antibodies.
  Kubo S, Ohtake N, Miyakawa K, Jeremiah SS, Yamaoka Y, Murohashi K, Hagiwara E, Mihara T, Goto A, Yamazaki E, Ogura T, Kaneko T, Yamanaka T, Ryo A. Front Microbiol. 2021 Jan 15;11:628281.

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• A longitudinal study on enteric virus contamination in bivalves along the coast of Ibaraki Prefecture, Japan. 
  Motoya T, Nagata N, Kashimura R, Ohashi K, Saito A, Osawa S, Goto K, Iwama S, Yanaoka T, Okayama K, Hirai S, Sugai T, Murakami K, Ishioka T, Ryo A, Katayama K, Kimura H. J Food Prot. 2021 Jan 7. doi: 10.4315/JFP-20-353. Epub ahead of print. PMID: 33411914.